PUBLICATIONS
RT-PCR and RAPID TEST
J. H. Soh, H.-M. Chan and J. Y. Ying, “Strategies for Developing Sensitive and Specific Nanoparticle-Based Lateral Flow Assays as Point-of-Care Diagnostic Device,” Nano Today, 30 (2020) 100831. Link
J. H. Soh, E. Balleza, M.N. Abdul Rahim, H. -M. Chan, S. Mohd Ali, J. K. C. Chuah, S. Edris, A. Atef, A. Bahieldin, J. Y. Ying, J. S. M. Sabir, “CRISPR-Based Systems for Sensitive and Rapid on-Site COVID-19 Diagnostics,” Trends in Biotechnology, 2022. DOI: 10.1016/j.tibtech.2022.06.002 Link
NANOPROBE ASSAYS
Y. Zu, M. H. Tan, E. C. Ren, J. Y. Ying, “Facile and Phase‐Defined Determination of HLA Alleles with Morpholino‐Functionalized Nanoparticle Probes,” Nanomedicine, 13[2] (2017) 611‐618 Link
Y. Zu, M.‐H. Tan, B. Chowbay, S. C. Lee, H. Yap, M. T. M. Lee, L.‐S. Lu, C.‐P. Chang, J. Y. Ying, “Nanoprobe‐Based Genetic Testing,” Nano Today, 9[2] (2014) 166‐171 Link
ACCURATE PREDICTION OF HUMAN ORGAN TOXICITY
F. Hussain, S. Basu, J. J. H. Heng, L.-H. Loo and D. Zink, “Predicting Direct Hepatocyte Toxicity in Humans by Combining High-Throughput Imaging of HepaRG Cells and Machine Learning-Based Phenotypic Profiling,” Archives of Toxicology, 94[8] (2020) 2749-2767. DOI:10.1007/s00204-020-02778-3 Link
K. Kandasamy, J. K. C. Chuah, R. Su, P. Huang, K. G. Eng, S. Xiong, Y. Li, C. S. Chia, L.-H. Loo and D. Zink, “Prediction of Drug-Induced Nephrotoxicity and Injury Mechanisms with Human Induced Pluripotent Stem Cell-Derived Cells and Machine Learning Methods,” Scientific Reports, 5 (2015) 12337. DOI:10.1038/srep12337 Link
L. T. M. van der Ven, E. Rorije, R. C. Sprong, D. Zink, R. Derr, G. Hendriks, L.-H. Loo and M. Lujiten, “A Case Study with Triazole Fungicides to Explore Practical Application of Next-Generation Hazard Assessment Methods for Human Health,” Chemical Research in Toxicology, 33[3] (2020) 834-848. DOI:10.1021/acs.chemrestox.9b00484 Link
R. Su, S. Xiong, D. Zink and L. -H. Loo, “High-Throughput Imaging-Based Nephrotoxicity Prediction for Xenobiotics with Diverse Chemical Structures,” Archives of Toxicology, 90[11] (2016) 2793-2808. DOI:10.1007/s00204-015-1638-y Link